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Netrin-1 and its receptor Unc5b are novel targets for the treatment of inflammatory arthritis

Rheumatoid arthritis is an autoimmune disease that is characterized by chronic inflammation and destruction of joints. Netrin-1, a chemorepulsant, laminin-like matrix protein, promotes inflammation by preventing macrophage egress from inflamed sites and is required for osteoclast differentiation. We...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Mediero, Aránzazu, Wilder, Tuere, Ramkhelawon, Bhama, Moore, Kathryn J., Cronstein, Bruce N.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067256/
https://ncbi.nlm.nih.gov/pubmed/27502509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600615R
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