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Netrin1 Is Highly Expressed And Required In Inflammatory Infiltrates In Wear Particle-Induced Osteolysis
OBJECTIVE: Netrin-1 is a chemorepulsant and matrix protein expressed during and required for osteoclast differentiation, which also plays a role in inflammation by preventing macrophage egress. Because wear particle-induced osteolysis requires osteoclast-mediated destruction of bone, we hypothesized...
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| Publié dans: | Ann Rheum Dis |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5349296/ https://ncbi.nlm.nih.gov/pubmed/26452536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-207593 |
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