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Direct or indirect stimulation of adenosine A(2A) receptors enhances bone regeneration as well as bone morphogenetic protein-2

Promoting bone regeneration and repair of bone defects is a need that has not been well met to date. We have previously found that adenosine, acting via A(2A) receptors (A2AR) promotes wound healing and inhibits inflammatory osteolysis and hypothesized that A2AR might be a novel target to promote bo...

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Detalles Bibliográficos
Publicado en:FASEB J
Main Authors: Mediero, Aránzazu, Wilder, Tuere, Perez-Aso, Miguel, Cronstein, Bruce N.
Formato: Artigo
Idioma:Inglês
Publicado: Federation of American Societies for Experimental Biology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396602/
https://ncbi.nlm.nih.gov/pubmed/25573752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-265066
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