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Direct or indirect stimulation of adenosine A(2A) receptors enhances bone regeneration as well as bone morphogenetic protein-2

Promoting bone regeneration and repair of bone defects is a need that has not been well met to date. We have previously found that adenosine, acting via A(2A) receptors (A2AR) promotes wound healing and inhibits inflammatory osteolysis and hypothesized that A2AR might be a novel target to promote bo...

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Bibliografiske detaljer
Udgivet i:FASEB J
Main Authors: Mediero, Aránzazu, Wilder, Tuere, Perez-Aso, Miguel, Cronstein, Bruce N.
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396602/
https://ncbi.nlm.nih.gov/pubmed/25573752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-265066
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