Welcome to the next step for Oncogenesis

di Medema, J P
Pubblicato in Oncogenesis (2014)

Human colonic fibroblasts regulate stemness and chemotherapy resistance of colon cancer stem cells

di Colak, S., Medema, J.P.
Pubblicato in Cell Cycle (2014)

Calcium inhibits epidermal growth factor-induced activation of p21ras in human primary keratinocytes.

di Medema, J P, Sark, M W, Backendorf, C, Bos, J L
Pubblicazione 1994

Betulinic acid-induced mitochondria-dependent cell death is counterbalanced by an autophagic salvage response

di Potze, L, Mullauer, F B, Colak, S, Kessler, J H, Medema, J P
Pubblicato in Cell Death Dis (2014)

Ex vivo culture of intestinal crypt organoids as a model system for assessing cell death induction in intestinal epithelial cells and enteropathy

di Grabinger, T, Luks, L, Kostadinova, F, Zimberlin, C, Medema, J P, Leist, M, Brunner, T
Pubblicazione 2014

Cyclopentenyl cytosine increases gemcitabine radiosensitisation in human pancreatic cancer cells

di van Bree, C, Rodermond, H M, Leen, R, Medema, J P, van Kuilenburg, A B P
Pubblicazione 2008

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

di Medema, J P, Scaffidi, C, Kischkel, F C, Shevchenko, A, Mann, M, Krammer, P H, Peter, M E
Pubblicazione 1997

Decreased mitochondrial priming determines chemoresistance of colon cancer stem cells

di Colak, S, Zimberlin, C D, Fessler, E, Hogdal, L, Prasetyanti, P R, Grandela, C M, Letai, A, Medema, J P
Pubblicazione 2014

Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer

di Kandimalla, R, Linnekamp, J F, van Hooff, S, Castells, A, Llor, X, Andreu, M, Jover, R, Goel, A, Medema, J P
Pubblicato in Oncogenesis (2017)

Circulating APRIL levels are correlated with advanced disease and prognosis in rectal cancer patients

di Lascano, V, Hahne, M, Papon, L, Cameron, K, Röeder, C, Schafmayer, C, Driessen, L, van Eenennaam, H, Kalthoff, H, Medema, J P
Pubblicato in Oncogenesis (2015)

Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity

di Vermeulen, L., Todaro, M., de Sousa Mello, F., Sprick, M. R., Kemper, K., Perez Alea, M., Richel, D. J., Stassi, G., Medema, J. P.
Pubblicazione 2008

An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK–APRIL fusion protein

di Pradet-Balade, B., Medema, J.P., López-Fraga, M., Lozano, J.C., Kolfschoten, G.M., Picard, A., Martínez-A., C., Garcia-Sanz, J.A., Hahne, M.
Pubblicazione 2002

Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa

di de Bruijn, M T, Raats, D A E, Hoogwater, F J H, van Houdt, W J, Cameron, K, Medema, J P, Borel Rinkes, I H M, Kranenburg, O
Pubblicazione 2010

The TNF family member APRIL promotes colorectal tumorigenesis

di Lascano, V, Zabalegui, L F, Cameron, K, Guadagnoli, M, Jansen, M, Burggraaf, M, Versloot, M, Rodermond, H, van der Loos, C, Carvalho-Pinto, C E, Kalthoff, H, Medema, J P, Hahne, M
Pubblicazione 2012

Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors

di Medema, J. P., de Jong, J., Peltenburg, L. T. C., Verdegaal, E. M. E., Gorter, A., Bres, S. A., Franken, K. L. M. C., Hahne, M., Albar, J. P., Melief, C. J. M., Offringa, R.
Pubblicazione 2001

Neoadjuvant chemotherapy affects molecular classification of colorectal tumors

di Trumpi, K, Ubink, I, Trinh, A, Djafarihamedani, M, Jongen, J M, Govaert, K M, Elias, S G, van Hooff, S R, Medema, J P, Lacle, M M, Vermeulen, L, Borel Rinkes, I H M, Kranenburg, O
Pubblicato in Oncogenesis (2017)

Interconnectivity between molecular subtypes and tumor stage in colorectal cancer

di Coebergh van den Braak, R. R. J., ten Hoorn, S., Sieuwerts, A. M., Tuynman, J. B., Smid, M., Wilting, S. M., Martens, J. W. M., Punt, C. J. A., Foekens, J. A., Medema, J. P., IJzermans, J. N. M., Vermeulen, L.
Pubblicato in BMC Cancer (2020)

A multidimensional network approach reveals microRNAs as determinants of the mesenchymal colorectal cancer subtype

di Fessler, E, Jansen, M, De Sousa E Melo, F, Zhao, L, Prasetyanti, P R, Rodermond, H, Kandimalla, R, Linnekamp, J F, Franitza, M, van Hooff, S R, de Jong, J H, Oppeneer, S C, van Noesel, C J M, Dekker, E, Stassi, G, Wang, X, Medema, J P, Vermeulen, L
Pubblicato in Oncogene (2016)

ADAM12 is a circulating marker for stromal activation in pancreatic cancer and predicts response to chemotherapy

di Veenstra, V. L., Damhofer, H., Waasdorp, C., van Rijssen, L. B., van de Vijver, M. J., Dijk, F., Wilmink, H. W., Besselink, M. G., Busch, O. R., Chang, D. K., Bailey, P. J., Biankin, A. V., Kocher, H. M., Medema, J. P., Li, J. S., Jiang, R., Pierce, D. W., van Laarhoven, H. W. M., Bijlsma, M. F.
Pubblicato in Oncogenesis (2018)

Improving clinical management of colon cancer through CONNECTION, a nation-wide colon cancer registry and stratification effort (CONNECTION II trial): rationale and protocol of a s...

di van den Berg, I., van de Weerd, S., Roodhart, J. M. L., Vink, G. R., van den Braak, R. R. J. Coebergh, Jimenez, C. R., Elias, S. G., van Vliet, D., Koelink, M., Hong, E., van Grevenstein, W. M. U., van Oijen, M. G. H., Beets-Tan, R. G. H., van Krieken, J. H. J. M., IJzermans, J. N. M., Medema, J. P., Koopman, M.
Pubblicato in BMC Cancer (2020)