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Cyclopentenyl cytosine increases gemcitabine radiosensitisation in human pancreatic cancer cells
The deoxycytidine analogue 2′,2′-difluoro-2′-deoxycytidine (dFdC, gemcitabine) is a potent radiosensitiser, but has limited efficacy in combination with radiotherapy in patients with pancreatic cancer due to acute toxicity. We investigated whether cyclopentenyl cytosine (CPEC), targetting the ‘de no...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2359636/ https://ncbi.nlm.nih.gov/pubmed/18349845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604287 |
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