The role of apoptotic cell death in the radiosensitising effect of gemcitabine

BACKGROUND: The aim of this study was to evaluate the radiosensitising effect of gemcitabine, in terms of cell-cycle progression, induction of apoptosis, and to investigate the molecular events regulating apoptosis. METHODS: Tumour cells were treated with gemcitabine, radiation, or the combination....

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Detalhes bibliográficos
Main Authors: Pauwels, B, Vermorken, J B, Wouters, A, Ides, J, Van Laere, S, Lambrechts, H A J, Pattyn, G G O, Vermeulen, K, Meijnders, P, Lardon, F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736812/
https://ncbi.nlm.nih.gov/pubmed/19672265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605145
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