Decreased mitochondrial priming determines chemoresistance of colon cancer stem cells

Tumor heterogeneity is in part determined by the existence of cancer stem cells (CSCs) and more differentiated tumor cells. CSCs are considered to be the tumorigenic root of cancers and suggested to be chemotherapy resistant. Here we exploited an assay that allowed us to measure chemotherapy-induced...

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Главные авторы: Colak, S, Zimberlin, C D, Fessler, E, Hogdal, L, Prasetyanti, P R, Grandela, C M, Letai, A, Medema, J P
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2014
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Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207483/
https://ncbi.nlm.nih.gov/pubmed/24682005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.37
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