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FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).
Upon activation, the apoptosis-inducing cell membrane receptor CD95 (APO-1/Fas) recruits a set of intracellular signaling proteins (CAP1-4) into a death-inducing signaling complex (DISC). In the DISC, CAP1 and CAP2 represent FADD/MORT1. CAP4 was identified recently as an ICE-like protease, FLICE, wi...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1997
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1169888/ https://ncbi.nlm.nih.gov/pubmed/9184224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.10.2794 |
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