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Dynamics within the CD95 death-inducing signaling complex decide life and death of cells
This study explores the dilemma in cellular signaling that triggering of CD95 (Fas/APO-1) in some situations results in cell death and in others leads to the activation of NF-κB. We established an integrated kinetic mathematical model for CD95-mediated apoptotic and NF-κB signaling. Systematic model...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2858442/ https://ncbi.nlm.nih.gov/pubmed/20212524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.6 |
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