Caspase-8 activity has an essential role in CD95/Fas-mediated MAPK activation

Stimulation of CD95/Fas/APO-1 results in the induction of both apoptotic and non-apoptotic signaling pathways. The processes regulating these two opposing pathways have not been thoroughly elucidated to date. In this study, using quantitative immunoblots, imaging, and mathematical modeling, we addre...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kober, A M M, Legewie, S, Pforr, C, Fricker, N, Eils, R, Krammer, P H, Lavrik, I N
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2011
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219090/
https://ncbi.nlm.nih.gov/pubmed/21975294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.93
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