Caspase-8 activity has an essential role in CD95/Fas-mediated MAPK activation

Stimulation of CD95/Fas/APO-1 results in the induction of both apoptotic and non-apoptotic signaling pathways. The processes regulating these two opposing pathways have not been thoroughly elucidated to date. In this study, using quantitative immunoblots, imaging, and mathematical modeling, we addre...

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Bibliographic Details
Main Authors:	Kober, A M M, Legewie, S, Pforr, C, Fricker, N, Eils, R, Krammer, P H, Lavrik, I N
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 2011
Subjects:	Original Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3219090/ https://ncbi.nlm.nih.gov/pubmed/21975294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.93
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Caspase-8 activity has an essential role in CD95/Fas-mediated MAPK activation

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