Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer

Stage II colon cancer (CC) still remains a clinical challenge with patient stratification for adjuvant therapy (AT) largely relying on clinical parameters. Prognostic biomarkers are urgently needed for better stratification. Previously, we have shown that WNT target genes AXIN2, DKK1, APCDD1, ASCL2...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Kandimalla, R, Linnekamp, J F, van Hooff, S, Castells, A, Llor, X, Andreu, M, Jover, R, Goel, A, Medema, J P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520503/
https://ncbi.nlm.nih.gov/pubmed/28368388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.9
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