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Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity
Aberrant activation of canonical Wingless-type MMTV integration site family (Wnt) signaling is pathognomonic of colorectal cancers (CRC) harboring functional mutations in either adenomatous polyposis coli or β-catenin. Coincident with Wnt cascade activation, CRCs also up-regulate the expression of W...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396472/ https://ncbi.nlm.nih.gov/pubmed/22745173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203015109 |
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