Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity

Aberrant activation of canonical Wingless-type MMTV integration site family (Wnt) signaling is pathognomonic of colorectal cancers (CRC) harboring functional mutations in either adenomatous polyposis coli or β-catenin. Coincident with Wnt cascade activation, CRCs also up-regulate the expression of W...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wu, Zhao-Qiu, Brabletz, Thomas, Fearon, Eric, Willis, Amanda L., Hu, Casey Yuexian, Li, Xiao-Yan, Weiss, Stephen J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3396472/
https://ncbi.nlm.nih.gov/pubmed/22745173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203015109
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