In This Issue, Volume 9, Issue 1

by Meanwell, Nicholas A.
Published in ACS Med Chem Lett (2018)

In This Issue, Volume 9, Issue 8

by Meanwell, Nicholas A.
Published in ACS Med Chem Lett (2018)

The Influence of Bioisosteres in Drug Design: Tactical Applications to Address Developability Problems

by Meanwell, Nicholas A.
Published in Tactics in Contemporary Drug Design (2014)

The Discovery and Development of Daclatasvir: An Inhibitor of the Hepatitis C Virus NS5A Replication Complex

by Meanwell, Nicholas A., Belema, Makonen
Published in HCV: The Journey from Discovery to a Cure (2018)

In Praise of Remarkably Powerful Centamolecular Therapeutic Agents

by Meanwell, Nicholas A., Ewing, William R.
Published in ACS Med Chem Lett (2019)

Severe acute respiratory syndrome coronavirus entry into host cells: Opportunities for therapeutic intervention

by Yeung, Kap‐Sun, Yamanaka, Gregory A., Meanwell, Nicholas A.
Published in Med Res Rev (2006)

Chapter 22. Non-HIV antiviral agents

by Meanwell, Nicholas A., Serrano-Wu, Michael H., Snyder, Lawrence B.
Published in Annu Rep Med Chem (2003)

Second Generation Inhibitors of HIV-1 Maturation

by Regueiro-Ren, Alicia, Dicker, Ira B., Hanumegowda, Umesh, Meanwell, Nicholas A.
Published in ACS Med Chem Lett (2019)

The Discovery and Early Clinical Evaluation of the HCV NS3/4A Protease Inhibitor Asunaprevir (BMS-650032)

by Meanwell, Nicholas A., Rajamani, Ramkumar, Scola, Paul M., Sun, Li-Qiang
Published in HCV: The Journey from Discovery to a Cure (2018)

The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors

by Lambert, Sebastian M, Langley, David R, Garnett, James A, Angell, Richard, Hedgethorne, Katy, Meanwell, Nicholas A, Matthews, Steve J
Published 2014

pH-Dependent Changes in Photoaffinity Labeling Patterns of the H1 Influenza Virus Hemagglutinin by Using an Inhibitor of Viral Fusion

by Cianci, Christopher, Yu, Kuo-Long, Dischino, Douglas D., Harte, William, Deshpande, Milind, Luo, Guangxiang, Colonno, Richard J., Meanwell, Nicholas A., Krystal, Mark
Published 1999

Homology models of the HIV-1 attachment inhibitor BMS-626529 bound to gp120 suggest a unique mechanism of action

by Langley, David R, Roy Kimura, S, Sivaprakasam, Prasanna, Zhou, Nannan, Dicker, Ira, McAuliffe, Brian, Wang, Tao, Kadow, John F, Meanwell, Nicholas A, Krystal, Mark
Published in Proteins (2015)

Targeting a binding pocket within the trimer-of-hairpins: Small-molecule inhibition of viral fusion

by Cianci, Christopher, Langley, David R., Dischino, Douglas D., Sun, Yaxiong, Yu, Kuo-Long, Stanley, Anne, Roach, Julia, Li, Zhufang, Dalterio, Richard, Colonno, Richard, Meanwell, Nicholas A., Krystal, Mark
Published 2004

Synergistic Activity of Combined NS5A Inhibitors

by O'Boyle, Donald R., Nower, Peter T., Gao, Min, Fridell, Robert, Wang, Chunfu, Hewawasam, Piyasena, Lopez, Omar, Tu, Yong, Meanwell, Nicholas A., Belema, Makonen, Roberts, Susan B., Cockett, Mark, Sun, Jin-Hua
Published in Antimicrob Agents Chemother (2016)

Mechanistic Studies and Modeling Reveal the Origin of Differential Inhibition of Gag Polymorphic Viruses by HIV-1 Maturation Inhibitors

by Lin, Zeyu, Cantone, Joseph, Lu, Hao, Nowicka-Sans, Beata, Protack, Tricia, Yuan, Tian, Yang, Hong, Liu, Zheng, Drexler, Dieter, Regueiro-Ren, Alicia, Meanwell, Nicholas A., Cockett, Mark, Krystal, Mark, Lataillade, Max, Dicker, Ira B.
Published in PLoS Pathog (2016)

Identification of Hepatitis C Virus NS5A Inhibitors

by Lemm, Julie A., O'Boyle, Donald, Liu, Mengping, Nower, Peter T., Colonno, Richard, Deshpande, Milind S., Snyder, Lawrence B., Martin, Scott W., St. Laurent, Denis R., Serrano-Wu, Michael H., Romine, Jeffrey L., Meanwell, Nicholas A., Gao, Min
Published 2010

Preclinical Profile and Characterization of the Hepatitis C Virus NS3 Protease Inhibitor Asunaprevir (BMS-650032)

by McPhee, Fiona, Sheaffer, Amy K., Friborg, Jacques, Hernandez, Dennis, Falk, Paul, Zhai, Guangzhi, Levine, Steven, Chaniewski, Susan, Yu, Fei, Barry, Diana, Chen, Chaoqun, Lee, Min S., Mosure, Kathy, Sun, Li-Qiang, Sinz, Michael, Meanwell, Nicholas A., Colonno, Richard J., Knipe, Jay, Scola, Paul
Published 2012

Biochemical and Genetic Characterizations of a Novel Human Immunodeficiency Virus Type 1 Inhibitor That Blocks gp120-CD4 Interactions

by Guo, Qi, Ho, Hsu-Tso, Dicker, Ira, Fan, Li, Zhou, Nannan, Friborg, Jacques, Wang, Tao, McAuliffe, Brian V., Wang, Hwei-gene Heidi, Rose, Ronald E., Fang, Hua, Scarnati, Helen T., Langley, David R., Meanwell, Nicholas A., Abraham, Ralph, Colonno, Richard J., Lin, Pin-fang
Published 2003

Discovery of Potent Hepatitis C Virus NS5A Inhibitors with Dimeric Structures

by Lemm, Julie A., Leet, John E., O'Boyle, Donald R., Romine, Jeffrey L., Huang, Xiaohua Stella, Schroeder, Daniel R., Alberts, Jeffrey, Cantone, Joseph L., Sun, Jin-Hua, Nower, Peter T., Martin, Scott W., Serrano-Wu, Michael H., Meanwell, Nicholas A., Snyder, Lawrence B., Gao, Min
Published 2011

Inhibitors of HCV NS5A: From Iminothiazolidinones to Symmetrical Stilbenes

by Romine, Jeffrey L., St. Laurent, Denis R., Leet, John E., Martin, Scott W., Serrano-Wu, Michael H., Yang, Fukang, Gao, Min, O’Boyle, Donald R, Lemm, Julie A., Sun, Jin-Hua, Nower, Peter T., Huang, Xiaohua (Stella), Deshpande, Milind S., Meanwell, Nicholas A., Snyder, Lawrence B.
Published 2011