Ebb and Tide of Glucokinase

Por Matschinsky, Franz M.
Publicado em 2001

Glucokinase activators (GKAs) promise a new pharmacotherapy for diabetics

Por Matschinsky, Franz M, Porte, Daniel
Publicado em 2010

The Central Role of Glucokinase in Glucose Homeostasis: A Perspective 50 Years After Demonstrating the Presence of the Enzyme in Islets of Langerhans

Por Matschinsky, Franz M., Wilson, David F.
Publicado no Front Physiol (2019)

Cerebrovascular Blood Flow Design and Regulation; Vulnerability in Aging Brain

Por Wilson, David F., Matschinsky, Franz M.
Publicado no Front Physiol (2020)

Kinetics of Insulin Release from the Perfused Rat Pancreas Caused by Glucose, Glucosamine, and Galactose

Por Landgraf, Rüdiger, Kotler-Brajtburg, Janina, Matschinsky, Franz M.
Publicado em 1971

Susceptibility of Glucokinase-MODY Mutants to Inactivation by Oxidative Stress in Pancreatic β-Cells

Por Cullen, Kirsty S., Matschinsky, Franz M., Agius, Loranne, Arden, Catherine
Publicado em 2011

The thermodynamic basis of glucose‐stimulated insulin release: a model of the core mechanism

Por Wilson, David F., Cember, Abigail T. J., Matschinsky, Franz M.
Publicado no Physiol Rep (2017)

Glucose Modulation of Amino Acid-Induced Glucagon and Insulin Release in the Isolated Perfused Rat Pancreas

Por Pagliara, Anthony S., Stillings, Susan N., Hover, Barbara, Martin, Duane M., Matschinsky, Franz M.
Publicado em 1974

Palmitic acid acutely inhibits acetylcholine- but not GLP-1-stimulated insulin secretion in mouse pancreatic islets

Por Doliba, Nicolai M., Qin, Wei, Vinogradov, Sergei A., Wilson, David F., Matschinsky, Franz M.
Publicado em 2010

Repair of diverse diabetic defects of β-cells in man and mouse by pharmacological glucokinase activation

Por Doliba, Nicolai M., Fenner, Deborah, Zelent, Bogumil, Bass, Joseph, Sarabu, Ramakanth, Matschinsky, Franz M.
Publicado no Diabetes Obes Metab (2012)

Regulation of insulin preRNA splicing by glucose

Por Wang, Juehu, Shen, Luping, Najafi, Habiba, Kolberg, Janice, Matschinsky, Franz M., Urdea, Mickey, German, Michael
Publicado em 1997

Analysis of gene expression in pancreatic islets from diet-induced obese mice

Por Imai, Yumi, Patel, Hiral R., Doliba, Nicolai M., Matschinsky, Franz M., Tobias, John W., Ahima, Rexford S.
Publicado em 2008

Effects of a glucokinase activator on hepatic intermediary metabolism: study with (13)C-isotopomer-based metabolomics

Por Nissim, Itzhak, Horyn, Oksana, Nissim, Ilana, Daikhin, Yevgeny, Wehrli, Suzanne L., Yudkoff, Marc, Matschinsky, Franz M.
Publicado em 2012

Inhibition of cholinergic potentiation of insulin secretion from pancreatic islets by chronic elevation of glucose and fatty acids: Protection by casein kinase 2 inhibitor

Por Doliba, Nicolai M., Liu, Qin, Li, Changhong, Chen, Pan, Liu, Chengyang, Naji, Ali, Matschinsky, Franz M.
Publicado no Mol Metab (2017)

The microRNA-21−PDCD4 axis prevents type 1 diabetes by blocking pancreatic β cell death

Por Ruan, Qingguo, Wang, Ting, Kameswaran, Vasumathi, Wei, Qin, Johnson, Derek S., Matschinsky, Franz, Shi, Weiyun, Chen, Youhai H.
Publicado em 2011

Analysis of the co-operative interaction between the allosterically regulated proteins GK and GKRP using tryptophan fluorescence

Por Zelent, Bogumil, Raimondo, Anne, Barrett, Amy, Buettger, Carol W., Chen, Pan, Gloyn, Anna L., Matschinsky, Franz M.
Publicado em 2014

Foxa2 regulates multiple pathways of insulin secretion

Por Lantz, Kristen A., Vatamaniuk, Marko Z., Brestelli, John E., Friedman, Joshua R., Matschinsky, Franz M., Kaestner, Klaus H.
Publicado em 2004

Exendin-(9–39) Corrects Fasting Hypoglycemia in SUR-1(–/–) Mice by Lowering cAMP in Pancreatic β-Cells and Inhibiting Insulin Secretion

Por De León, Diva D., Li, Changhong, Delson, Madeleine I., Matschinsky, Franz M., Stanley, Charles A., Stoffers, Doris A.
Publicado em 2008

Glucokinase Activators for Diabetes Therapy: May 2010 status report

Por Matschinsky, Franz M., Zelent, Bogumil, Doliba, Nicolai, Li, Changhong, Vanderkooi, Jane M., Naji, Ali, Sarabu, Ramakanth, Grimsby, Joseph
Publicado em 2011

Alterations of Pancreatic Islet Structure, Metabolism and Gene Expression in Diet-Induced Obese C57BL/6J Mice

Por Roat, Regan, Rao, Vandana, Doliba, Nicolai M., Matschinsky, Franz M., Tobias, John W., Garcia, Eden, Ahima, Rexford S., Imai, Yumi
Publicado em 2014