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The thermodynamic basis of glucose‐stimulated insulin release: a model of the core mechanism

A model for glucose sensing by pancreatic β‐cells is developed and compared with the available experimental data. The model brings together mathematical representations for the activities of the glucose sensor, glucokinase, and oxidative phosphorylation. Glucokinase produces glucose 6‐phosphate (G‐6...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Wilson, David F., Cember, Abigail T. J., Matschinsky, Franz M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5492210/
https://ncbi.nlm.nih.gov/pubmed/28655753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13327
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