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A kinetic core model of the glucose-stimulated insulin secretion network of pancreatic β cells
The construction and characterization of a core kinetic model of the glucose-stimulated insulin secretion system (GSIS) in pancreatic β cells is described. The model consists of 44 enzymatic reactions, 59 metabolic state variables, and 272 parameters. It integrates five subsystems: glycolysis, the T...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer New York
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1998884/ https://ncbi.nlm.nih.gov/pubmed/17514510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-007-9011-y |
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