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Palmitic acid acutely inhibits acetylcholine- but not GLP-1-stimulated insulin secretion in mouse pancreatic islets

Fatty acids, acetylcholine, and GLP-1 enhance insulin secretion in a glucose-dependent manner. However, the interplay between glucose, fatty acids, and the neuroendocrine regulators of insulin secretion is not well understood. Therefore, we studied the acute effects of PA (alone or in combination wi...

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Detalhes bibliográficos
Main Authors: Doliba, Nicolai M., Qin, Wei, Vinogradov, Sergei A., Wilson, David F., Matschinsky, Franz M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944283/
https://ncbi.nlm.nih.gov/pubmed/20606076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00072.2010
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