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Palmitic acid acutely inhibits acetylcholine- but not GLP-1-stimulated insulin secretion in mouse pancreatic islets

Fatty acids, acetylcholine, and GLP-1 enhance insulin secretion in a glucose-dependent manner. However, the interplay between glucose, fatty acids, and the neuroendocrine regulators of insulin secretion is not well understood. Therefore, we studied the acute effects of PA (alone or in combination wi...

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Bibliografske podrobnosti
Main Authors: Doliba, Nicolai M., Qin, Wei, Vinogradov, Sergei A., Wilson, David F., Matschinsky, Franz M.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944283/
https://ncbi.nlm.nih.gov/pubmed/20606076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00072.2010
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