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Palmitic acid acutely inhibits acetylcholine- but not GLP-1-stimulated insulin secretion in mouse pancreatic islets

Fatty acids, acetylcholine, and GLP-1 enhance insulin secretion in a glucose-dependent manner. However, the interplay between glucose, fatty acids, and the neuroendocrine regulators of insulin secretion is not well understood. Therefore, we studied the acute effects of PA (alone or in combination wi...

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Bibliographische Detailangaben
Hauptverfasser: Doliba, Nicolai M., Qin, Wei, Vinogradov, Sergei A., Wilson, David F., Matschinsky, Franz M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944283/
https://ncbi.nlm.nih.gov/pubmed/20606076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00072.2010
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