טוען...
The microRNA-21−PDCD4 axis prevents type 1 diabetes by blocking pancreatic β cell death
Death of pancreatic β cells is a pathological hallmark of type 1 diabetes (T1D). However, the molecular mechanisms of β cell death and its regulation are poorly understood. Here we describe a unique regulatory pathway of β cell death that comprises microRNA-21, its target tumor suppressor PDCD4, and...
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Main Authors: | , , , , , , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
National Academy of Sciences
2011
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141944/ https://ncbi.nlm.nih.gov/pubmed/21730150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1101450108 |
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