Th2 Cell Therapy of Established Acute Graft-Versus-Host Disease Requires IL-4 and IL-10 and Is Abrogated by IL-2 or Host-type Antigen-Presenting-Cells

Por Foley, Jason E., Mariotti, Jacopo, Ryan, Kaitlyn, Eckhaus, Michael, Fowler, Daniel H.
Publicado em 2008

Graft rejection as a Th1-type process amenable to regulation by donor Th2-type cells through an interleukin-4/STAT6 pathway

Por Mariotti, Jacopo, Foley, Jason, Ryan, Kaitlyn, Buxhoeveden, Nicole, Kapoor, Veena, Amarnath, Shoba, Fowler, Daniel H.
Publicado em 2008

Rapamycin delays growth of Wnt-1 tumors in spite of suppression of host immunity

Por Svirshchevskaya, Elena V, Mariotti, Jacopo, Wright, Mollie H, Viskova, Natalia Y, Telford, William, Fowler, Daniel H, Varticovski, Lyuba
Publicado em 2008

STAT3 Transcription Factor Promotes Instability of nTreg Cells and Limits Generation of iTreg Cells During Acute Murine Graft Versus Host Disease

Por Laurence, Arian, Amarnath, Shoba, Mariotti, Jacopo, Kim, Yong Chan, Foley, Jason, Eckhaus, Michael, O’Shea, John J., Fowler, Daniel H.
Publicado em 2012

The Pentostatin Plus Cyclophosphamide (PC) Non-myeloablative Regimen Induces Durable Host T Cell Functional Deficits and Prevents Murine Marrow Allograft Rejection

Por Mariotti, Jacopo, Taylor, Justin, Massey, Paul R., Ryan, Kaitlyn, Foley, Jason, Buxhoeveden, Nicole, Felizardo, Tania C., Amarnath, Shoba, Mossoba, Miriam E., Fowler, Daniel H.
Publicado em 2010

Rapamycin generates anti-apoptotic human Th1/Tc1 cells via autophagy for induction of xenogeneic GVHD

Por Amarnath, Shoba, Flomerfelt, Francis A., Costanzo, Carliann M., Foley, Jason E., Mariotti, Jacopo, Konecki, Daniel M., Gangopadhyay, Anu, Eckhaus, Michael, Wong, Susan, Levine, Bruce L., June, Carl H., Fowler, Daniel H.
Publicado em 2010

Regulatory T Cells and Human Myeloid Dendritic Cells Promote Tolerance via Programmed Death Ligand-1

Por Amarnath, Shoba, Costanzo, Carliann M., Mariotti, Jacopo, Ullman, Jessica L., Telford, William G., Kapoor, Veena, Riley, James L., Levine, Bruce L., June, Carl H., Fong, Timothy, Warner, Noel L., Fowler, Daniel H.
Publicado em 2010

Potent induction of B- and T-cell immunity against human carcinoembryonic antigen-expressing tumors in human carcinoembryonic antigen transgenic mice mediated by direct lentivector...

Por Loisel-Meyer, Severine, Felizardo, Tania, Mariotti, Jacopo, Mossoba, Miriam E., Foley, Jason E., Kammerer, Robert, Mizue, Nobuo, Keefe, Robert, McCart, J. Andrea, Zimmermann, Wolfgang, Dropulic, Boro, Fowler, Daniel H., Medin, Jeffrey A.
Publicado em 2009

A Central Role for Foxp3+ Regulatory T Cells in K-Ras-Driven Lung Tumorigenesis

Por Granville, Courtney A., Memmott, Regan M., Balogh, Andria, Mariotti, Jacopo, Kawabata, Shigeru, Han, Wei, LoPiccolo, Jaclyn, Foley, Jason, Liewehr, David J., Steinberg, Seth M., Fowler, Daniel H., Hollander, M. Christine, Dennis, Phillip A.
Publicado em 2009

Phase 2 clinical trial of rapamycin-resistant donor CD4(+) Th2/Th1 (T-Rapa) cells after low-intensity allogeneic hematopoietic cell transplantation

Por Fowler, Daniel H., Mossoba, Miriam E., Steinberg, Seth M., Halverson, David C., Stroncek, David, Khuu, Hahn M., Hakim, Frances T., Castiello, Luciano, Sabatino, Marianna, Leitman, Susan F., Mariotti, Jacopo, Gea-Banacloche, Juan C., Sportes, Claude, Hardy, Nancy M., Hickstein, Dennis D., Pavletic, Steven Z., Rowley, Scott, Goy, Andre, Donato, Michele, Korngold, Robert, Pecora, Andrew, Levine, Bruce L., June, Carl H., Gress, Ronald E., Bishop, Michael R.
Publicado em 2013

High-Dose Sirolimus And Immune Selective Pentostatin Plus Cyclophosphamide Conditioning Yields Stable Mixed Chimerism and Insufficient Graft-Versus-Tumor Responses

Por Mossoba, Miriam E., Halverson, David C., Kurlander, Roger, Schuver, Bazetta Blacklock, Carpenter, Ashley, Hansen, Brenna, Steinberg, Seth M., Ali, Syed Abbas, Tageja, Nishant, Hakim, Frances T., Gea-Banacloche, Juan, Sportes, Claude, Hardy, Nancy M., Hickstein, Dennis D., Pavletic, Steven Z., Khuu, Hanh, Sabatini, Marianna, Stroncek, David, Levine, Bruce L., June, Carl H., Mariotti, Jacopo, Rixe, Olivier, Fojo, Antonio Tito, Bishop, Michael R., Gress, Ronald. E., Fowler, Daniel H.
Publicado no Clin Cancer Res (2015)