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STAT3 Transcription Factor Promotes Instability of nTreg Cells and Limits Generation of iTreg Cells During Acute Murine Graft Versus Host Disease
Acute graft versus host disease (GvHD) is a major cause of mortality in allogeneic bone marrow transplantation (BMT), for which administration of FoxP3(+) Treg cells has been proposed as a therapy. However, the phenotypic stability of Treg cells is controversial and cytokines that signal through the...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3441059/ https://ncbi.nlm.nih.gov/pubmed/22921119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.05.027 |
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