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tTregs, pTregs, and iTregs: Similarities and Differences

Foxp3(+) T-regulatory cells (Tregs) are primarily generated in the thymus (tTreg), but also may be generated extrathymically at peripheral sites (pTreg), or induced in cell culture (iTreg) in the presence of transforming growth factor β (TGFβ). A major unresolved issue is how these different populat...

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Détails bibliographiques
Auteurs principaux: Shevach, Ethan M, Thornton, Angela M
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982187/
https://ncbi.nlm.nih.gov/pubmed/24712461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12160
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