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tTregs, pTregs, and iTregs: Similarities and Differences

Foxp3(+) T-regulatory cells (Tregs) are primarily generated in the thymus (tTreg), but also may be generated extrathymically at peripheral sites (pTreg), or induced in cell culture (iTreg) in the presence of transforming growth factor β (TGFβ). A major unresolved issue is how these different populat...

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Detalles Bibliográficos
Main Authors: Shevach, Ethan M, Thornton, Angela M
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982187/
https://ncbi.nlm.nih.gov/pubmed/24712461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12160
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