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Helios Deficiency Predisposes the Differentiation of CD4(+)Foxp3(−) T Cells into pTregs

The transcription factor Helios is expressed in a large percentage of Foxp3(+) regulatory T cells (Tregs) and is required for the maintenance of their suppressive phenotype as mice with a selective deficiency of Helios in Tregs spontaneously develop autoimmunity. However, mice with a deficiency of H...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunol
Prif Awduron: Skadow, Mathias, Penna, Vinay R., Galant-Swafford, Jessica, Shevach, Ethan M., Thornton, Angela M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615958/
https://ncbi.nlm.nih.gov/pubmed/31167776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900388
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