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Helios Deficiency Predisposes the Differentiation of CD4(+)Foxp3(−) T Cells into pTregs
The transcription factor Helios is expressed in a large percentage of Foxp3(+) regulatory T cells (Tregs) and is required for the maintenance of their suppressive phenotype as mice with a selective deficiency of Helios in Tregs spontaneously develop autoimmunity. However, mice with a deficiency of H...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6615958/ https://ncbi.nlm.nih.gov/pubmed/31167776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900388 |
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