Single-Cell Sequencing Reveals the Transcriptome and TCR Characteristics of pTregs and in vitro Expanded iTregs

Regulatory T cells (Tregs) play a critical role in the maintenance of immune tolerance and tumor evasion. However, the relative low proportion of these cells in peripheral blood and tissues has hindered many studies. We sought to establish a rapamycin-based in vitro Treg expansion procedure in patie...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hui, Zhenzhen, Zhang, Jiali, Zheng, Yu, Yang, Lili, Yu, Wenwen, An, Yang, Wei, Feng, Ren, Xiubao
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044526/
https://ncbi.nlm.nih.gov/pubmed/33868236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.619932
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