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High TCR Stimuli Prevent iTreg Differentiation in an NF-κB-Dependent Manner()
The concentration of antigen or mitogenic stimuli is known to play an important role in controlling the differentiation of naïve CD4(+) T cells into different effector phenotypes. In particular, whereas TCR engagement at low antigen doses in the presence of TGF-β and IL-2 can promote differentiation...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544303/ https://ncbi.nlm.nih.gov/pubmed/21411734 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002361 |
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