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T cell-NF-κB activation is required for tumor control in vivo

BACKGROUND: T cells have the capacity to eliminate tumors but the signaling pathways by which they do so are incompletely understood. T cell priming requires activation of the transcription factors AP-1, NFAT and NF-κB downstream of the TCR, but whether activation of T cell-NF-κB in vivo is required...

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Библиографические подробности
Опубликовано в: :J Immunother Cancer
Главные авторы: Barnes, Sarah E, Wang, Ying, Chen, Luqiu, Molinero, Luciana L, Gajewski, Thomas F, Evaristo, Cesar, Alegre, Maria-Luisa
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308877/
https://ncbi.nlm.nih.gov/pubmed/25648675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-014-0045-x
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