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T cell-NF-κB activation is required for tumor control in vivo
BACKGROUND: T cells have the capacity to eliminate tumors but the signaling pathways by which they do so are incompletely understood. T cell priming requires activation of the transcription factors AP-1, NFAT and NF-κB downstream of the TCR, but whether activation of T cell-NF-κB in vivo is required...
Shranjeno v:
| izdano v: | J Immunother Cancer |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4308877/ https://ncbi.nlm.nih.gov/pubmed/25648675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-014-0045-x |
| Oznake: |
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