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T cell-NF-κB activation is required for tumor control in vivo

BACKGROUND: T cells have the capacity to eliminate tumors but the signaling pathways by which they do so are incompletely understood. T cell priming requires activation of the transcription factors AP-1, NFAT and NF-κB downstream of the TCR, but whether activation of T cell-NF-κB in vivo is required...

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書目詳細資料
發表在:J Immunother Cancer
Main Authors: Barnes, Sarah E, Wang, Ying, Chen, Luqiu, Molinero, Luciana L, Gajewski, Thomas F, Evaristo, Cesar, Alegre, Maria-Luisa
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308877/
https://ncbi.nlm.nih.gov/pubmed/25648675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-014-0045-x
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