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T cell receptor/CARMA1/NF-κB signaling controls T-helper (Th) 17 differentiation
IL-17–producing CD4 T cells play a key role in immune responses against extracellular bacteria and autoimmunity. Nuclear factor κB (NF-κB) is required for T-cell activation and selected effector functions, but its role in Th17 differentiation is controversial. Using genetic mouse models that impede...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494911/ https://ncbi.nlm.nih.gov/pubmed/23091043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1204557109 |
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