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Fas Mediates Cardiac Allograft Acceptance in Mice with Impaired T Cell-Intrinsic NF-κB Signaling
The transcription factor NF-κB is critical for T cell activation and survival. We have shown that mice expressing a T cell-restricted NF-κB superrepressor (IκBαΔN-Tg) permanently accept heart but not skin allografts. Overexpression of the prosurvival factor Bcl-x(L) in T cells restored heart rejecti...
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| Publicado no: | Transpl Int |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4423812/ https://ncbi.nlm.nih.gov/pubmed/19351347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1432-2277.2009.00875.x |
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