Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations

Por LoPiccolo, Jaclyn, Blumenthal, Gideon M., Bernstein, Wendy B., Dennis, Phillip A.
Publicado em 2007

Prognostic significance of clinical factors and Akt activation in patients with bronchioloalveolar carcinoma

Por Tsurutani, Junji, Steinberg, Seth M., Ballas, Marc, Robertson, Matthew, LoPiccolo, Jaclyn, Soda, Hiroshi, Kohno, Shigeru, Egilsson, Valgardur, Dennis, Phillip A.
Publicado em 2006

Rac1-stimulated macropinocytosis enhances Gβγ activation of PI3Kβ

Por Erami, Zahra, Khalil, Bassem D., Salloum, Gilbert, Yao, Yanhua, LoPiccolo, Jaclyn, Shymanets, Aliaksei, Nürnberg, Bernd, Bresnick, Anne R., Backer, Jonathan M.
Publicado no Biochem J (2017)

Different inhibition of Gβγ-stimulated class I(B) phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody: Specific function of p101 as a Gβγ-dependent regulator of PI3K...

Por Shymanets, Aliaksei, Prajwal, Vadas, Oscar, Czupalla, Cornelia, LoPiccolo, Jaclyn, Brenowitz, Michael, Ghigo, Alessandra, Hirsch, Emilio, Krause, Eberhard, Wetzker, Reinhard, Williams, Roger L., Harteneck, Christian, Nürnberg, Bernd
Publicado no Biochem J (2015)

Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer

Por LoPiccolo, Jaclyn, Kim, Seung Joong, Shi, Yi, Wu, Bin, Wu, Haiyan, Chait, Brian T., Singer, Robert H., Sali, Andrej, Brenowitz, Michael, Bresnick, Anne R., Backer, Jonathan M.
Publicado no J Biol Chem (2015)

A Central Role for Foxp3+ Regulatory T Cells in K-Ras-Driven Lung Tumorigenesis

Por Granville, Courtney A., Memmott, Regan M., Balogh, Andria, Mariotti, Jacopo, Kawabata, Shigeru, Han, Wei, LoPiccolo, Jaclyn, Foley, Jason, Liewehr, David J., Steinberg, Seth M., Fowler, Daniel H., Hollander, M. Christine, Dennis, Phillip A.
Publicado em 2009

A phase I trial of the HIV protease inhibitor nelfinavir in adults with solid tumors

Por Blumenthal, Gideon M., Gills, Joell J., Ballas, Marc S., Bernstein, Wendy B., Komiya, Takefumi, Dechowdhury, Roopa, Morrow, Betsy, Root, Hyejeong, Chun, Guinevere, Helsabeck, Cynthia, Steinberg, Seth M., LoPiccolo, Jaclyn, Kawabata, Shigeru, Gardner, Erin R., Figg, William D., Dennis, Phillip A.
Publicado no Oncotarget (2014)