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Rapamycin delays growth of Wnt-1 tumors in spite of suppression of host immunity

BACKGROUND: Rapamycin, an inhibitor of mammalian target of Rapamycin (mTOR), is an immunosuppressive agent that has anti-proliferative effects on some tumors. However, the role of Rapamycin-induced immune suppression on tumor progression has not been examined. METHODS: We developed a transplantation...

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Detalhes bibliográficos
Main Authors: Svirshchevskaya, Elena V, Mariotti, Jacopo, Wright, Mollie H, Viskova, Natalia Y, Telford, William, Fowler, Daniel H, Varticovski, Lyuba
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453140/
https://ncbi.nlm.nih.gov/pubmed/18570671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-176
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