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Rapamycin suppresses brain aging in senescence-accelerated OXYS rats

Cellular and organismal aging are driven in part by the MTOR (mechanistic target of rapamycin) pathway and rapamycin extends life span in C elegans, Drosophila and mice. Herein, we investigated effects of rapamycin on brain aging in OXYS rats. Previously we found, in OXYS rats, an early development...

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Main Authors: Kolosova, Nataliya G., Vitovtov, Anton O., Muraleva, Natalia A, Akulov, Andrey E., Stefanova, Natalia A., Blagosklonny, Mikhail V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824413/
https://ncbi.nlm.nih.gov/pubmed/23817674
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