Serine 77 in the PDZ domain of PICK1 is a protein kinase Cα phosphorylation site regulated by lipid membrane binding

by Ammendrup-Johnsen, Ina, Thorsen, Thor S., Gether, Ulrik, Madsen, Kenneth L.
Published 2012

Early Stage Alpha-Synuclein Amyloid Fibrils are Reservoirs of Membrane-Binding Species

by Skamris, Thomas, Marasini, Carlotta, Madsen, Kenneth L., Foderà, Vito, Vestergaard, Bente
Published in Sci Rep (2019)

Protein Interacting with C Kinase 1 (PICK1) Reduces Reinsertion Rates of Interaction Partners Sorted to Rab11-dependent Slow Recycling Pathway

by Madsen, Kenneth L., Thorsen, Thor S., Rahbek-Clemmensen, Troels, Eriksen, Jacob, Gether, Ulrik
Published 2012

Functional Modulation of the Glutamate Transporter Variant GLT1b by the PDZ Domain Protein PICK1

by Sogaard, Rikke, Borre, Lars, Braunstein, Thomas H., Madsen, Kenneth L., MacAulay, Nanna
Published 2013

Reply to Wilkinson et al.: Concerning the use of pHluorin-tagged GluA2 as a reporter for NMDA-induced AMPA receptor recycling

by Rathje, Mette, Fang, Huaqiang, Bachman, Julia L., Gether, Ulrik, Huganir, Richard L., Madsen, Kenneth L.
Published 2014

Differential Internalization Rates and Postendocytic Sorting of the Norepinephrine and Dopamine Transporters Are Controlled by Structural Elements in the N Termini

by Vuorenpää, Anne, Jørgensen, Trine N., Newman, Amy H., Madsen, Kenneth L., Scheinin, Mika, Gether, Ulrik
Published in J Biol Chem (2016)

Amphipathic motifs in BAR domains are essential for membrane curvature sensing

by Bhatia, Vikram K, Madsen, Kenneth L, Bolinger, Pierre-Yves, Kunding, Andreas, Hedegård, Per, Gether, Ulrik, Stamou, Dimitrios
Published 2009

AMPA receptor pHluorin-GluA2 reports NMDA receptor-induced intracellular acidification in hippocampal neurons

by Rathje, Mette, Fang, Huaqiang, Bachman, Julia L., Anggono, Victor, Gether, Ulrik, Huganir, Richard L., Madsen, Kenneth L.
Published 2013

Protein Interacting with C-kinase 1 (PICK1) Binding Promiscuity Relies on Unconventional PSD-95/Discs-Large/ZO-1 Homology (PDZ) Binding Modes for Nonclass II PDZ Ligands

by Erlendsson, Simon, Rathje, Mette, Heidarsson, Pétur O., Poulsen, Flemming M., Madsen, Kenneth L., Teilum, Kaare, Gether, Ulrik
Published 2014

The BAR Domain Protein PICK1 Controls Vesicle Number and Size in Adrenal Chromaffin Cells

by Pinheiro, Paulo S., Jansen, Anna M., de Wit, Heidi, Tawfik, Bassam, Madsen, Kenneth L., Verhage, Matthijs, Gether, Ulrik, Sørensen, Jakob B.
Published 2014

Structure–activity relationships of a small-molecule inhibitor of the PDZ domain of PICK1

by Bach, Anders, Stuhr-Hansen, Nicolai, Thorsen, Thor S., Bork, Nicolai, Moreira, Irina S., Frydenvang, Karla, Padrah, Shahrokh, Christensen, S. Brøgger, Madsen, Kenneth L., Weinstein, Harel, Gether, Ulrik, Strømgaard, Kristian
Published 2010

Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1

by Bassan, Merav, Liu, Hongguang, Madsen, Kenneth L., Armsen, Wencke, Zhou, Jiayi, DeSilva, Tara, Chen, Weizhi, Paradise, Allison, Brasch, Michael A., Staudinger, Jeff, Gether, Ulrik, Irwin, Nina, Rosenberg, Paul A.
Published in Eur J Neurosci (2008)

Membrane Localization is Critical for Activation of the PICK1 BAR Domain

by Madsen, Kenneth L., Eriksen, Jacob, Milan-Lobo, Laura, Han, Daniel S., Niv, Masha Y., Ammendrup-Johnsen, Ina, Henriksen, Ulla, Bhatia, Vikram K., Stamou, Dimitrios, Sitte, Harald H., McMahon, Harvey T., Weinstein, Harel, Gether, Ulrik
Published 2008

Membrane-permeable C-terminal Dopamine Transporter Peptides Attenuate Amphetamine-evoked Dopamine Release

by Rickhag, Mattias, Owens, William A., Winkler, Marie-Therese, Strandfelt, Kristine Nørgaard, Rathje, Mette, Sørensen, Gunnar, Andresen, Bjørn, Madsen, Kenneth L., Jørgensen, Trine Nygaard, Wörtwein, Gitta, Woldbye, David P. D., Sitte, Harald, Daws, Lynette C., Gether, Ulrik
Published 2013

Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD

by Thorsen, Thor S., Madsen, Kenneth L., Rebola, Nelson, Rathje, Mette, Anggono, Victor, Bach, Anders, Moreira, Irina S., Stuhr-Hansen, Nicolai, Dyhring, Tino, Peters, Dan, Beuming, Thijs, Huganir, Richard, Weinstein, Harel, Mulle, Christophe, Strømgaard, Kristian, Rønn, Lars Christian B., Gether, Ulrik
Published 2009

A C-terminal PDZ domain binding sequence is required for striatal distribution of the dopamine transporter

by Rickhag, Mattias, Hansen, Freja Herborg, Sørensen, Gunnar, Strandfelt, Kristine Nørgaard, Andresen, Bjørn, Gotfryd, Kamil, Madsen, Kenneth L., Vestergaard-Klewe, Ib, Ammendrup-Johnsen, Ina, Eriksen, Jacob, Füchtbauer, Ernst-Martin, Gomeza, Jesus, Woldbye, David P.D., Wörtwein, Gitta, Gether, Ulrik
Published 2013

PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis

by Jensen, Kathrine Louise, Sørensen, Gunnar, Dencker, Ditte, Owens, William Anthony, Rahbek-Clemmensen, Troels, Brett Lever, Michael, Runegaard, Annika H., Riis Christensen, Nikolaj, Weikop, Pia, Wörtwein, Gitta, Fink-Jensen, Anders, Madsen, Kenneth L., Daws, Lynette, Gether, Ulrik, Rickhag, Mattias
Published in eNeuro (2018)

PICK1 Deficiency Impairs Secretory Vesicle Biogenesis and Leads to Growth Retardation and Decreased Glucose Tolerance

by Holst, Birgitte, Madsen, Kenneth L., Jansen, Anna M., Jin, Chunyu, Rickhag, Mattias, Lund, Viktor K., Jensen, Morten, Bhatia, Vikram, Sørensen, Gunnar, Madsen, Andreas N., Xue, Zhichao, Møller, Siri K., Woldbye, David, Qvortrup, Klaus, Huganir, Richard, Stamou, Dimitrios, Kjærulff, Ole, Gether, Ulrik
Published 2013

Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-ray scattering

by Karlsen, Morten L., Thorsen, Thor S., Johner, Niklaus, Ammendrup-Johnsen, Ina, Erlendsson, Simon, Tian, Xinsheng, Simonsen, Jens B., Høiberg-Nielsen, Rasmus, Christensen, Nikolaj M., Khelashvili, George, Streicher, Werner, Teilum, Kaare, Vestergaard, Bente, Weinstein, Harel, Gether, Ulrik, Arleth, Lise, Madsen, Kenneth L.
Published in Structure (2015)

A high‐affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain

by Christensen, Nikolaj R, De Luca, Marta, Lever, Michael B, Richner, Mette, Hansen, Astrid B, Noes‐Holt, Gith, Jensen, Kathrine L, Rathje, Mette, Jensen, Dennis Bo, Erlendsson, Simon, Bartling, Christian RO, Ammendrup‐Johnsen, Ina, Pedersen, Sofie E, Schönauer, Michèle, Nissen, Klaus B, Midtgaard, Søren R, Teilum, Kaare, Arleth, Lise, Sørensen, Andreas T, Bach, Anders, Strømgaard, Kristian, Meehan, Claire F, Vægter, Christian B, Gether, Ulrik, Madsen, Kenneth L
Published in EMBO Mol Med (2020)