PICK1-Deficient Mice Exhibit Impaired Response to Cocaine and Dysregulated Dopamine Homeostasis

Protein interacting with C-kinase 1 (PICK1) is a widely expressed scaffold protein known to interact via its PSD-95/discs-large/ZO-1 (PDZ)-domain with several membrane proteins including the dopamine (DA) transporter (DAT), the primary target for cocaine’s reinforcing actions. Here, we establish the...

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Enregistré dans:
Détails bibliographiques
Publié dans:eNeuro
Auteurs principaux: Jensen, Kathrine Louise, Sørensen, Gunnar, Dencker, Ditte, Owens, William Anthony, Rahbek-Clemmensen, Troels, Brett Lever, Michael, Runegaard, Annika H., Riis Christensen, Nikolaj, Weikop, Pia, Wörtwein, Gitta, Fink-Jensen, Anders, Madsen, Kenneth L., Daws, Lynette, Gether, Ulrik, Rickhag, Mattias
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2018
Sujets:
New Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001137/
https://ncbi.nlm.nih.gov/pubmed/29911172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0422-17.2018
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