Amphipathic motifs in BAR domains are essential for membrane curvature sensing

BAR (Bin/Amphiphysin/Rvs) domains and amphipathic α-helices (AHs) are believed to be sensors of membrane curvature thus facilitating the assembly of protein complexes on curved membranes. Here, we used quantitative fluorescence microscopy to compare the binding of both motifs on single nanosized lip...

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Autori principali: Bhatia, Vikram K, Madsen, Kenneth L, Bolinger, Pierre-Yves, Kunding, Andreas, Hedegård, Per, Gether, Ulrik, Stamou, Dimitrios
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776096/
https://ncbi.nlm.nih.gov/pubmed/19816406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.261
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