Amphipathic motifs in BAR domains are essential for membrane curvature sensing

BAR (Bin/Amphiphysin/Rvs) domains and amphipathic α-helices (AHs) are believed to be sensors of membrane curvature thus facilitating the assembly of protein complexes on curved membranes. Here, we used quantitative fluorescence microscopy to compare the binding of both motifs on single nanosized lip...

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Main Authors: Bhatia, Vikram K, Madsen, Kenneth L, Bolinger, Pierre-Yves, Kunding, Andreas, Hedegård, Per, Gether, Ulrik, Stamou, Dimitrios
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2009
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776096/
https://ncbi.nlm.nih.gov/pubmed/19816406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.261
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