Amphipathic motifs in BAR domains are essential for membrane curvature sensing

BAR (Bin/Amphiphysin/Rvs) domains and amphipathic α-helices (AHs) are believed to be sensors of membrane curvature thus facilitating the assembly of protein complexes on curved membranes. Here, we used quantitative fluorescence microscopy to compare the binding of both motifs on single nanosized lip...

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Detalhes bibliográficos
Main Authors: Bhatia, Vikram K, Madsen, Kenneth L, Bolinger, Pierre-Yves, Kunding, Andreas, Hedegård, Per, Gether, Ulrik, Stamou, Dimitrios
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776096/
https://ncbi.nlm.nih.gov/pubmed/19816406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.261
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