Amphipathic motifs in BAR domains are essential for membrane curvature sensing

BAR (Bin/Amphiphysin/Rvs) domains and amphipathic α-helices (AHs) are believed to be sensors of membrane curvature thus facilitating the assembly of protein complexes on curved membranes. Here, we used quantitative fluorescence microscopy to compare the binding of both motifs on single nanosized lip...

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Hauptverfasser: Bhatia, Vikram K, Madsen, Kenneth L, Bolinger, Pierre-Yves, Kunding, Andreas, Hedegård, Per, Gether, Ulrik, Stamou, Dimitrios
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776096/
https://ncbi.nlm.nih.gov/pubmed/19816406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.261
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