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Structure of dimeric and tetrameric complexes of the BAR domain protein PICK1 determined by small-angle X-ray scattering

PICK1 is a neuronal scaffolding protein containing a PDZ domain and an autoinhibited BAR domain. BAR domains are membrane-sculpting protein modules generating membrane curvature and promoting membrane fission. Previous data suggest that BAR domains are organized in lattice-like arrangements when sta...

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Bibliographic Details
Published in:Structure
Main Authors: Karlsen, Morten L., Thorsen, Thor S., Johner, Niklaus, Ammendrup-Johnsen, Ina, Erlendsson, Simon, Tian, Xinsheng, Simonsen, Jens B., Høiberg-Nielsen, Rasmus, Christensen, Nikolaj M., Khelashvili, George, Streicher, Werner, Teilum, Kaare, Vestergaard, Bente, Weinstein, Harel, Gether, Ulrik, Arleth, Lise, Madsen, Kenneth L.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502314/
https://ncbi.nlm.nih.gov/pubmed/26073603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.04.020
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