Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets

PDZ domain scaffold proteins are molecular modules orchestrating cellular signalling in space and time. Here, we investigate assembly of PDZ scaffolds using supported cell membrane sheets, a unique experimental setup enabling direct access to the intracellular face of the cell membrane. Our data dem...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Erlendsson, Simon, Thorsen, Thor Seneca, Vauquelin, Georges, Ammendrup-Johnsen, Ina, Wirth, Volker, Martinez, Karen L, Teilum, Kaare, Gether, Ulrik, Madsen, Kenneth Lindegaard
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Biochemistry and Chemical Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345565/
https://ncbi.nlm.nih.gov/pubmed/30605082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39180
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