Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets

PDZ domain scaffold proteins are molecular modules orchestrating cellular signalling in space and time. Here, we investigate assembly of PDZ scaffolds using supported cell membrane sheets, a unique experimental setup enabling direct access to the intracellular face of the cell membrane. Our data dem...

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Bibliographic Details
Published in:eLife
Main Authors: Erlendsson, Simon, Thorsen, Thor Seneca, Vauquelin, Georges, Ammendrup-Johnsen, Ina, Wirth, Volker, Martinez, Karen L, Teilum, Kaare, Gether, Ulrik, Madsen, Kenneth Lindegaard
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2019
Subjects:
Biochemistry and Chemical Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345565/
https://ncbi.nlm.nih.gov/pubmed/30605082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39180
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