Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets

PDZ domain scaffold proteins are molecular modules orchestrating cellular signalling in space and time. Here, we investigate assembly of PDZ scaffolds using supported cell membrane sheets, a unique experimental setup enabling direct access to the intracellular face of the cell membrane. Our data dem...

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Enregistré dans:
Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Erlendsson, Simon, Thorsen, Thor Seneca, Vauquelin, Georges, Ammendrup-Johnsen, Ina, Wirth, Volker, Martinez, Karen L, Teilum, Kaare, Gether, Ulrik, Madsen, Kenneth Lindegaard
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2019
Sujets:
Biochemistry and Chemical Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345565/
https://ncbi.nlm.nih.gov/pubmed/30605082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39180
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