Differential Internalization Rates and Postendocytic Sorting of the Norepinephrine and Dopamine Transporters Are Controlled by Structural Elements in the N Termini

The norepinephrine transporter (NET) mediates reuptake of synaptically released norepinephrine in central and peripheral noradrenergic neurons. The molecular processes governing availability of NET in the plasma membrane are poorly understood. Here we use the fluorescent cocaine analogue JHC 1-64, a...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Vuorenpää, Anne, Jørgensen, Trine N., Newman, Amy H., Madsen, Kenneth L., Scheinin, Mika, Gether, Ulrik
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Neurobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4786704/
https://ncbi.nlm.nih.gov/pubmed/26786096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702050
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