The Serotonin Transporter Undergoes Constitutive Internalization and Is Primarily Sorted to Late Endosomes and Lysosomal Degradation

The serotonin transporter (SERT) plays a critical role in regulating serotonin signaling by mediating reuptake of serotonin from the extracellular space. The molecular and cellular mechanisms controlling SERT levels in the membrane remain poorly understood. To study trafficking of the surface reside...

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Autors principals: Rahbek-Clemmensen, Troels, Bay, Tina, Eriksen, Jacob, Gether, Ulrik, Jørgensen, Trine Nygaard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Neurobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132800/
https://ncbi.nlm.nih.gov/pubmed/24973209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.495754
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