Structural insights into the activation of MST3 by MO25

Por Mehellou, Youcef, Alessi, Dario R., Macartney, Thomas J., Szklarz, Marta, Knapp, Stefan, Elkins, Jonathan M.
Publicado em 2013

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K(+)–Cl(−) co-transporters

Por delos Heros, Paola, Alessi, Dario R., Gourlay, Robert, Campbell, David G., Deak, Maria, Macartney, Thomas J., Kahle, Kristopher T., Zhang, Jinwei
Publicado em 2014

The CUL3–KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt intera...

Por Ohta, Akihito, Schumacher, Frances-Rose, Mehellou, Youcef, Johnson, Clare, Knebel, Axel, Macartney, Thomas J., Wood, Nicola T., Alessi, Dario R., Kurz, Thimo
Publicado em 2013

Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction

Por vanderWijst, Jenny, Blanchard, Maxime G., Woodroof, Helen I., Macartney, Thomas J., Gourlay, Robert, Hoenderop, Joost G., Bindels, René J., Alessi, Dario R.
Publicado em 2014

Cooperative Control of Holliday Junction Resolution and DNA Repair by the SLX1 and MUS81-EME1 Nucleases

Por Castor, Dennis, Nair, Nidhi, Déclais, Anne-Cécile, Lachaud, Christophe, Toth, Rachel, Macartney, Thomas J., Lilley, David M.J., Arthur, J.Simon C., Rouse, John
Publicado em 2013

PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

Por Kondapalli, Chandana, Kazlauskaite, Agne, Zhang, Ning, Woodroof, Helen I., Campbell, David G., Gourlay, Robert, Burchell, Lynn, Walden, Helen, Macartney, Thomas J., Deak, Maria, Knebel, Axel, Alessi, Dario R., Muqit, Miratul M. K.
Publicado em 2012

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

Por Lai, Yu‐Chiang, Kondapalli, Chandana, Lehneck, Ronny, Procter, James B, Dill, Brian D, Woodroof, Helen I, Gourlay, Robert, Peggie, Mark, Macartney, Thomas J, Corti, Olga, Corvol, Jean‐Christophe, Campbell, David G, Itzen, Aymelt, Trost, Matthias, Muqit, Miratul MK
Publicado no EMBO J (2015)