Cooperative Control of Holliday Junction Resolution and DNA Repair by the SLX1 and MUS81-EME1 Nucleases

Holliday junctions (HJs) are X-shaped DNA structures that arise during homologous recombination, which must be removed to enable chromosome segregation. The SLX1 and MUS81-EME1 nucleases can both process HJs in vitro, and they bind in close proximity on the SLX4 scaffold, hinting at possible coopera...

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Main Authors: Castor, Dennis, Nair, Nidhi, Déclais, Anne-Cécile, Lachaud, Christophe, Toth, Rachel, Macartney, Thomas J., Lilley, David M.J., Arthur, J.Simon C., Rouse, John
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808987/
https://ncbi.nlm.nih.gov/pubmed/24076219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.08.036
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