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Cleavage mechanism of human Mus81–Eme1 acting on Holliday-junction structures

Recombination-mediated repair plays a central role in maintaining genomic integrity during DNA replication. The human Mus81–Eme1 endonuclease is involved in recombination repair, but the exact structures it acts on in vivo are not known. Using kinetic and enzymatic analysis of highly purified recomb...

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Bibliografische gegevens
Hoofdauteurs: Taylor, Ewan R., McGowan, Clare H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268786/
https://ncbi.nlm.nih.gov/pubmed/18310322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710291105
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