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Cleavage mechanism of human Mus81–Eme1 acting on Holliday-junction structures

Recombination-mediated repair plays a central role in maintaining genomic integrity during DNA replication. The human Mus81–Eme1 endonuclease is involved in recombination repair, but the exact structures it acts on in vivo are not known. Using kinetic and enzymatic analysis of highly purified recomb...

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Hlavní autoři: Taylor, Ewan R., McGowan, Clare H.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268786/
https://ncbi.nlm.nih.gov/pubmed/18310322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710291105
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