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Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates?

The Holliday junction (HJ) is a central intermediate of homologous recombination. Its cleavage is critical for the formation of crossover recombinants during meiosis, which in turn helps to establish chiasmata and promote genetic diversity. Enzymes that cleave HJs, called HJ resolvases, have been id...

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Detalhes bibliográficos
Main Authors: Gaskell, Louise J, Osman, Fekret, Gilbert, Robert J C, Whitby, Matthew C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847671/
https://ncbi.nlm.nih.gov/pubmed/17363897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601645
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