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Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates?

The Holliday junction (HJ) is a central intermediate of homologous recombination. Its cleavage is critical for the formation of crossover recombinants during meiosis, which in turn helps to establish chiasmata and promote genetic diversity. Enzymes that cleave HJs, called HJ resolvases, have been id...

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Détails bibliographiques
Auteurs principaux: Gaskell, Louise J, Osman, Fekret, Gilbert, Robert J C, Whitby, Matthew C
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847671/
https://ncbi.nlm.nih.gov/pubmed/17363897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601645
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