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Mus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates?

The Holliday junction (HJ) is a central intermediate of homologous recombination. Its cleavage is critical for the formation of crossover recombinants during meiosis, which in turn helps to establish chiasmata and promote genetic diversity. Enzymes that cleave HJs, called HJ resolvases, have been id...

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Hlavní autoři: Gaskell, Louise J, Osman, Fekret, Gilbert, Robert J C, Whitby, Matthew C
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847671/
https://ncbi.nlm.nih.gov/pubmed/17363897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601645
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