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Cleavage mechanism of human Mus81–Eme1 acting on Holliday-junction structures
Recombination-mediated repair plays a central role in maintaining genomic integrity during DNA replication. The human Mus81–Eme1 endonuclease is involved in recombination repair, but the exact structures it acts on in vivo are not known. Using kinetic and enzymatic analysis of highly purified recomb...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268786/ https://ncbi.nlm.nih.gov/pubmed/18310322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710291105 |
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