Exploring intermediate cell states through the lens of single cells

door MacLean, Adam L., Hong, Tian, Nie, Qing
Gepubliceerd in Curr Opin Syst Biol (2018)

The ecology in the hematopoietic stem cell niche determines the clinical outcome in chronic myeloid leukemia

door MacLean, Adam L., Filippi, Sarah, Stumpf, Michael P. H.
Gepubliceerd in 2014

Cell lineage and communication network inference via optimization for single-cell transcriptomics

door Wang, Shuxiong, Karikomi, Matthew, MacLean, Adam L, Nie, Qing
Gepubliceerd in Nucleic Acids Res (2019)

scEpath: energy landscape-based inference of transition probabilities and cellular trajectories from single-cell transcriptomic data

door Jin, Suoqin, MacLean, Adam L, Peng, Tao, Nie, Qing
Gepubliceerd in Bioinformatics (2018)

Population dynamics of normal and leukaemia stem cells in the haematopoietic stem cell niche show distinct regimes where leukaemia will be controlled

door MacLean, Adam L., Lo Celso, Cristina, Stumpf, Michael P. H.
Gepubliceerd in 2013

Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia

door Crowell, Helena L., MacLean, Adam L., Stumpf, Michael P.H.
Gepubliceerd in J Theor Biol (2016)

Parameter-free methods distinguish Wnt pathway models and guide design of experiments

door MacLean, Adam L., Rosen, Zvi, Byrne, Helen M., Harrington, Heather A.
Gepubliceerd in Proc Natl Acad Sci U S A (2015)

Cellular population dynamics control the robustness of the stem cell niche

door MacLean, Adam L., Kirk, Paul D. W., Stumpf, Michael P. H.
Gepubliceerd in Biol Open (2015)

Epithelial-Mesenchymal Transition in Metastatic Cancer Cell Populations Affects Tumor Dormancy in a Simple Mathematical Model

door MacLean, Adam L., Harrington, Heather A., Stumpf, Michael P. H., Hansen, Marc D. H.
Gepubliceerd in Biomedicines (2014)

A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions

door Peng, Tao, Liu, Linan, MacLean, Adam L, Wong, Chi Wut, Zhao, Weian, Nie, Qing
Gepubliceerd in BMC Syst Biol (2017)

Transcriptomics reveals complex kinetics of dorsal-ventral patterning gene expression in the mandibular arch

door Sharma, Praveer P., MacLean, Adam L., Meinecke, Lina, Clouthier, David E., Nie, Qing, Schilling, Thomas F.
Gepubliceerd in Genesis (2018)

Bayesian inference of agent-based models: a tool for studying kidney branching morphogenesis

door Lambert, Ben, MacLean, Adam L., Fletcher, Alexander G., Combes, Alexander N., Little, Melissa H., Byrne, Helen M.
Gepubliceerd in J Math Biol (2018)

An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation

door Haensel, Daniel, Sun, Peng, MacLean, Adam L, Ma, Xianghui, Zhou, Yuan, Stemmler, Marc P, Brabletz, Simone, Berx, Geert, Plikus, Maksim V, Nie, Qing, Brabletz, Thomas, Dai, Xing
Gepubliceerd in EMBO Rep (2018)

Systematic tracking of altered haematopoiesis during sporozoite-mediated malaria development reveals multiple response points

door Vainieri, Maria L., Blagborough, Andrew M., MacLean, Adam L., Haltalli, Myriam L. R., Ruivo, Nicola, Fletcher, Helen A., Stumpf, Michael P. H., Sinden, Robert E., Lo Celso, Cristina
Gepubliceerd in Open Biol (2016)

Defining Epidermal Basal Cell States during Skin Homeostasis and Wound Healing Using Single-Cell Transcriptomics

door Haensel, Daniel, Jin, Suoqin, Sun, Peng, Cinco, Rachel, Dragan, Morgan, Nguyen, Quy, Cang, Zixuan, Gong, Yanwen, Vu, Remy, MacLean, Adam L., Kessenbrock, Kai, Gratton, Enrico, Nie, Qing, Dai, Xing
Gepubliceerd in Cell Rep (2020)

Single cell transcriptomics of human epidermis identifies basal stem cell transition states

door Wang, Shuxiong, Drummond, Michael L., Guerrero-Juarez, Christian F., Tarapore, Eric, MacLean, Adam L., Stabell, Adam R., Wu, Stephanie C., Gutierrez, Guadalupe, That, Bao T., Benavente, Claudia A., Nie, Qing, Atwood, Scott X.
Gepubliceerd in Nat Commun (2020)

Pathogenesis, Symptomatology, and Transmission of SARS-CoV-2 through Analysis of Viral Genomics and Structure

door Rando, Halie M., MacLean, Adam L., Lee, Alexandra J., Lordan, Ronan, Ray, Sandipan, Bansal, Vikas, Skelly, Ashwin N., Sell, Elizabeth, Dziak, John J., Shinholster, Lamonica, McGowan, Lucy D’Agostino, Guebila, Marouen Ben, Wellhausen, Nils, Knyazev, Sergey, Boca, Simina M., Capone, Stephen, Qi, Yanjun, Park, YoSon, Sun, Yuchen, Mai, David, Boerckel, Joel D, Brueffer, Christian, Byrd, James Brian, Kamil, Jeremy P., Wang, Jinhui, Velazquez, Ryan, Szeto, Gregory L, Barton, John P., Goel, Rishi Raj, Mangul, Serghei, Lubiana, Tiago, Gitter, Anthony, Greene, Casey S.
Gepubliceerd in ArXiv (2021)