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Population dynamics of normal and leukaemia stem cells in the haematopoietic stem cell niche show distinct regimes where leukaemia will be controlled

Haematopoietic stem cells (HSCs) are responsible for maintaining immune cells, red blood cells and platelets throughout life. HSCs must be located in their ecological niche (the bone marrow) to function correctly, that is, to regenerate themselves and their progeny; the latter eventually exit the bo...

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Detalhes bibliográficos
Main Authors: MacLean, Adam L., Lo Celso, Cristina, Stumpf, Michael P. H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627104/
https://ncbi.nlm.nih.gov/pubmed/23349436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2012.0968
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